Unpublished MSc thesis, University of North Texas Health Science Center, 2006/05, 89, type of study: ,rct,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Full text    (https://dialog.proquest.com/professional/pqdtprof)

Keywords:

immune system [53]
OMT [3925]
osteopathic manipulative treatment [3946]
pilot study [216]
randomized controlled trial [947]

Abstract:

Objectives. The purpose of this pilot study was to investigate the immediate effects of Osteopathic Manipulative Treatment (OMT) on immune function in a healthy population. Methods. This was a randomized, blinded and controlled clinical trial. 50 healthy individuals, ages 18 to 40, were recruited. Subjects were randomly assigned to one of two groups: OMT or Rest (control). Blood and saliva samples were collected pre and post-intervention (thirty minutes of OMT or Rest). Samples were analyzed for a CBC, salivary IgA, and various lymphocyte populations. Results. This study successfully demonstrated the feasibility of this protocol. No statistically significant differences in outcome measures were identified between the two groups, nor were any apparent trends identified. Conclusion. This established a framework for future research investigating the effects of OMT on acute and chronic infection, chronic pain, and immunocompromised populations in human and/or animal populations.