European Journal of Obstetrics and Gynecology and Reproductive Biology, 2024/02, 29394. doi: 10.1016/j.ejogrb.2023.08.265, type of study: ,css,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Full text    (https://www.ejog.org/article/S0301-2115(23)00571-7/abstract)

Keywords:

conference abstract [127]
cross sectional study [894]
female [654]
infertility [22]
OMT [3924]
osteopathic manipulative treatment [3945]
PCOS [6]
polycystic ovary syndrome [12]
women [607]

Abstract:

Introduction and aim of the study: The novel potential therapeutic strategies are needed for infertile and pregnant polycystic ovarysyndrome (PCOS) women. Due to therapeutic doubts, more anti-inflammation approaches in PCOS treatment, especially during the COVID pandemic, are considered. Low-grade inflammation is a recognized factor causing metabolic disorders in PCOS and a core feature of COVID-19 pathobiology. The osteopathic manipulative treatment (OMT) activates the cholinergic anti-inflammatory pathway (CAP) and can inhibit proinflammatory cytokines, such as TNF, IL-1β, and TNF-α. In our paper we analyzed the influence of OMT in women with PCOS. Methods: Seventy-three patients, aged 29–46, with a history of reproductive failure who underwent a physiotherapeutic treatment, were evaluated. Six months after the end of a physiotherapy session, a follow-up questionnaire was performed. Results: The results show that the majority of women (83.6%) were satisfied with the therapeutic process and that the sessions met the patient’s expectations. Reducing the level of anxiety related to infertility treatment and pregnancy was declared by n = 60 (82.2%) women, an improvement in well-being was declared by n = 72 (97.3%), and increasing awareness of the body after physiotherapy sessions was declared by n = 70 (95.9%) women. A statistically significant improvement in well-being was also observed in women who had a greater number (10–30) of therapeutic sessions (p = 0.04). Conclusions: The physiotherapeutic sessions enhanced quality of life and had a positive effect on overall health.