International Journal of Osteopathic Medicine, 2011/09, 14(3):96-105. doi: 10.1016/j.ijosm.2010.12.002, type of study: ,cct,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Full text    (http://www.sciencedirect.com/science/article/pii/S1746068910001380)

Keywords:

chronic fatigue syndrome [16]
manual therapy [6]
isometric quadriceps muscle testing [1]
EMG median frequency [1]
controlled clinical trial [324]

Abstract:

Objectives The objective of this study was to evaluate the efficacy of a manual treatment protocol for CFS/ME sufferers. Methods Isometric testing and EMG of the knee extensor muscles were conducted alongside the Profile of Fatigue Related States questionnaire. Subjects 9 patients suffering from CFS/ME, 9 age and gender-matched CFS/ME sufferers who were allowed to choose any treatment other than manual therapy and 9 age and gender-matched healthy volunteers were assessed at 0 and 12 months. Results Significant increases in peak and impulse torque were found which corresponded to improvements in the Profile of Fatigue Related States questionnaire in the treatment group only, no other significant changes were found. Conclusions These findings suggest that post-exercise muscle function in CFS/ME is improved following specialised osteopathic intervention. The authors suggest the reduction of lymphatic drainage to be a possible aetiological factor in the observed muscle fatigue.