The AAO Journal, 2023/06, 33(2):28. doi: 10.53702/2375-5717-33.2.20, type of study: ,cr,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Free full text   (https://meridian.allenpress.com/aaoj/article/33/2/20/493544/LBORC-NUFA-Poster-Abstracts-2023-Students)

Keywords:

abdominal pain [23]
anorexia [7]
appetite [2]
case report [736]
glioblastoma multiforme [1]
male [861]
OMT [3925]
osteopathic manipulative treatment [3946]
weight [22]

Abstract:

Introduction/Background: We present the case of a 53-year-old male diagnosed with glioblastoma multiforme (GBM) and his eventual decision for only osteopathic manipulative treatment (OMT). Glioblastoma multiforme (GBM) is a fast-growing tumor of astrocyte cells in the central nervous system. Case: Initial presentation to the emergency department on 08/21/21 was suspicious for seizure or stroke, with magnetic resonance imaging of the head performed 8/28/21 supporting a diagnosis of GBM. Chemoradiation with Temozolomide was implemented 10/06/21 - 11/24/21, followed by adjuvant treatment using Temozolomide from 12/15/21 - 04/19/22. The patient lost appetite for food during this treatment, and reduced eating led to a decrease in weight from 210 pounds on 08/21/21 to 156 lbs during the first OMT on 04/19/22. Results: Despite therapy, imaging on 04/11/22 demonstrated tumor enlargement. Given the disease progression, the patient elected to discontinue radiation and pharmaceutical therapies. Therefore, the patient’s only medical treatment from 4/19/22 to 8/19/22 was OMT consisting of visceral manipulation, myofascial release, soft tissue, and lymphatic techniques directed to the celiac, superior mesenteric, and inferior mesenteric ganglia. Appointment weights were 152 pounds, 147 pounds, 154 pounds, and 166 pounds at respective, chronological one-month follow-ups. This weight re-gain demonstrates the effect of OMT in promoting appetite and feelings of wellness. Discussion: The patient endorses increased appetite, alleviation of stomach cramping, and weight gain following OMT sessions. This case supports the use of OMT techniques to promote appetite and improve patient-reported wellness in a patient with GBM.