The Journal of the American Osteopathic Association, 2005/07, 105(7):320. doi: 10.7556/jaoa.2005.105.7.317, type of study: ,ccs,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Full text    (https://www.degruyter.com/document/doi/10.7556/jaoa.2005.105.7.317/html)

Keywords:

case control study [58]
diabetes [54]
diagnosis [412]
palpation [217]

Abstract:

Hypothesis: Osteopathic palpatory findings may represent viscerosomatic manifestations of disease. This study was performed to identify such findings associated with type 2 diabetes mellitus. Methods: A case-control study of 93 subjects was conducted at the University of North Texas Health Science Center during 2002-2003. Standardized osteopathic palpatory examinations were performed by predoctoral osteopathic manipulative medicine fellows who were blinded to each subject’s case control status. These examinations determined the presence or absence of skin changes, trophic changes, tissue changes, tenderness, and immobility at spinal segments T5-T7, T8-T10, and T11-L2 on either the left or right side. Multiple logistic regression was used to compute age- and sex-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for osteopathic palpatory findings associated with type 2 diabetes mellitus. Results: Three osteopathic palpatory findings were significantly associated with type 2 diabetes mellitus: tissue changes at T11-L2 on the right side (OR, 4.49; 95% CI, 1.69-11.96; P=.003); tenderness at T11-L2 on the left side (OR, 4.28; 95% CI, 1.13-16.20; P=.03); and immobility at T5-T7 on the right side (OR, 2.71; 95% CI, 1.09-6.75; P=.03). Conclusions: The observed associations must be interpreted in light of the complex pathogenesis and progression of type 2 diabetes mellitus. Additional research is warranted to replicate these findings in a prospective manner and to determine if, and how, these osteopathic palpatory findings are caused by type 2 diabetes mellitus.