The AAO Journal, 2024/06, 34(2):12-13. doi: 10.53702/i2375-5717-34.2.7, type of study: ,obs,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Full text    (https://meridian.allenpress.com/aaoj/article/34/2/7/500955/LBORC-NUFA-Poster-Abstracts-2024-Clinician-amp)

Keywords:

adolescents [23]
children [321]
observational study [246]
OMT [3925]
osteopathic manipulative treatment [3946]
pediatrics [573]
sickle cell disease [4]

Abstract:

Background: Children and adolescent young adults (CAYAs) with sickle cell disease (SCD) suffer from severe pain, resulting in hospitalization and diminished quality of life. With substantial morbidity conferred by SCD-related pain, improved supportive therapies are needed. Osteopathic manipulative treatment (OMT) is a potentially valuable adjunctive therapy. Hypothesis: OMT is safe and feasible for hospitalized CAYAs with SCD. Research Design: Prospective, single institution, observational study evaluating CAYAs with SCD aged 3-26 years hospitalized at Riley Hospital for Children. IRB approval was obtained. Interim analysis included data obtained December 2022-July 2023. Methods: Patients who reported pain were offered OMT. Verbal informed consent/assent were obtained. OMT was provided by trained osteopathic medical students under the supervision of a board-certified osteopathic physician. Safety was assessed by adverse event grading and pain by validated pain FACES scale. Feasibility endpoints were calculated as the percentage of OMT encounters offered and completed without interruption to inpatient care. Data were summarized using descriptive statistics. Results: Eight patients received OMT, with 32 separate encounters and 60 unique areas of pain treated. Majority of patients were male (n=5, 62.5%) with median age 17.5 years (range 6.8-23.5 years). All OMT encounters offered were completed without care interruption. No adverse events occurred within 24 hours of OMT. Median FACES scores pre-/post-OMT were 9 and 7.5, respectively. FACES scores post-OMT were decreased (n=22, 68.8%) or unchanged (n=10, 31.3%) in all encounters. 100% of patients surveyed reported interest in OMT for future pain management. Conclusion: OMT for hospitalized CAYAs with SCD is safe and feasible at interim analysis. The majority of patients had decreased pain following OMT. Findings support continued investigation into the potential efficacy of incorporating OMT into multimodal management of CAYAs with SCD.