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Masqueraders: how to identify atypical diabetes in primary care

Journal: Journal of Osteopathic Medicine Date: 2021/12, 121(12):Pages: 899–904. doi: Subito , type of study: article

Free full text   (https://www.degruyterbrill.com/document/doi/10.1515/jom-2021-0129/html)

Keywords:

article [2567]
atypical diabetes [1]
diabetes mellitus [29]
diagnosis [398]
primary care [66]

Abstract:

Diabetes mellitus is a complex set of conditions that impacts 34 million Americans. While type 1 diabetes, type 2 diabetes, and gestational diabetes are most frequently encountered, there are many other types of diabetes with which healthcare providers are less familiar. These atypical forms of diabetes make up nearly 10% of diabetes cases and can masquerade as type 1 or 2 diabetes mellitus (T1DM or T2DM), and the treatment may not be optimized if the diagnosis is not accurate. Atypical forms include monogenic diabetes (formally known as maturity-onset diabetes of the young [MODY]), latent autoimmune diabetes of the adult (LADA), ketosis-prone diabetes, and secondary diabetes. This paper will detail the defining characteristics of each atypical form and demonstrate how they can masquerade as type 1 or 2 diabetes mellitus. Gestational diabetes mellitus will not be discussed in this article.


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