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CV-4 Induced Physiological Change as Measured by Transcutaneous Laser Doppler Flowmeter

Journal: The Journal of the American Osteopathic Association Date: 2006/08, 106(8):Pages: 475. doi: Subito , type of study: pretest posttest design

Full text    (https://www.degruyter.com/document/doi/10.7556/jaoa.2006.106.8.471/html)

Keywords:

autonomic nervous system [142]
cranio-sacral osteopathy [223]
CV4 technique [14]
physiology [51]
pretest posttest design [217]

Abstract:

Background: Osteopathic manipulation techniques, such as Compression of the Fourth Ventricle (CV4), influence autonomic balance. Prior studies demonstrate that laser Doppler flowmeter (LDF) accurately measures autonomic balance by measuring the Traube-Hering (TH) wave (.08-.15 Hz) of peripheral blood flow velocity. Authors investigated the ability of CV4 technique to alter autonomic balance. Objective: To evaluate whether the CV4 technique alters autonomic balance as measured by the LDF in comparison to rest and touch (sham) only. Methods: 25 healthy subjects (convenience sample) gave informed consent to participate. LDF measured skin blood flow velocity before, during and after the CV4 technique. 18/25 subjects experienced both a sham and a CV4 technique, 7 experienced a CV4 only. Lying horizontal, a five min. baseline was recorded, followed by a five min. sham procedure, five min. resting interval, five min. CV4 technique and a final five min. post technique resting period. Three minutes of data were selected from each time frame. A spectral analysis was performed using DFT for each time frame and compared to other time frames using a paired sample t-test. Results: There is a significant difference in autonomic balance during the CV4 (P<.000). There is no significant difference between the baseline and post technique autonomic balance (P<.645), nor between baseline and the sham procedure (P<.727), or between the sham procedure and post technique (P<.630). The 08-.15 Hz component of blood flow velocity greatly decreased in amplitude in 24/25 subjects during a CV4 technique. The duration of altered autonomic balance during the CV4 was also longer than any change in autonomic balance measured at rest, during sham, or after the interventions (P<.000). Mean time frame of decreased amplitude of TH wave during CV4 is 64.6 seconds, compared to 11.68 seconds during rest and 14.92 seconds for sham. Conclusion: Decreased autonomic balance and its duration during CV4 are measurable and distinctly related to the technique. The LDF can quantify the therapeutic intervention known as the CV4 technique and differentiate its characteristic physiologic effect from resting state and sham interventions.


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