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Upon the neuronal supply of the human interosseous membrane of the forearm

Journal: The AAO Journal Date: 2024/06, 34(2):Pages: 14-15. doi: Subito , type of study: observational study

Full text    (https://meridian.allenpress.com/aaoj/article/34/2/7/500955/LBORC-NUFA-Poster-Abstracts-2024-Clinician-amp)

Keywords:

arm [57]
interosseous membrane [2]
observational study [227]
proprioception [16]

Abstract:

Introduction: The interosseous membrane of the forearm (IOM) has been researched especially for its biomechanical function. Recently, mechanoreceptors have been discovered in the IOM, indicating that its sensory role in proprioception has been largely underestimated. The forearm is crucial for everyday tasks, and injury to the forearm can be limiting. Objectives: This study aims to explore the IOM and its surrounding tissues for mechanoreceptors as well as for sympathetic innervation. Methods and Results: We excised a cross-sectional piece of the proximal, medial, and distal parts of 14 IOMs of seven donors, three males, and four females. These portions were processed and histologically and partially immunohistologically stained. Then, these sections were scanned and analysed. Mechanoreceptors were classified according to their original descriptions. The Kruskal-Wallis test and the Mann-Whitney-U test were performed. In 29 out of 42 IOM sections, mechanoreceptors were identified. However, in all sections, mechanoreceptors were identified in the surrounding tissues. In the IOM, Ruffini bodies, muscle spindles, Golgi-Tendon organs, and Vater-Pacini corpuscles were found. In addition, some sympathetic nerves were discovered within the IOM. In the tissues at the border to the IOM and surrounding the IOM Ruffini bodies, muscle spindles, Vater-Pacini corpuscles, and Golgi-Mazzoni corpuscles were discovered. Particularly interesting is the number of Golgi-Mazzoni corpuscles discovered. These are a subvariety of Vater-Pacini corpuscles composed of two or more axons with corresponding capsules. Conclusions: These findings prove that the IOM plays an important role in proprioception. Contrary to the current belief of having a solely stabilising function, the central band of the IOM and its surroundings are also richly innervated by mechanoreceptors. Therefore, we recommend considering the IOM and its surroundings as important proprioceptive structures.


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