Advanced search


Search results        Search results      Copy URL to E-Mail


Modifying functional brain networks in focal epilepsy by manual visceral-osteopathic stimulation of the vagus nerve at the abdomen

Journal: Frontiers in Network Physiology Date: 2023/07, 3(online 2023/07/13):Pages: 1205476. doi: Subito , type of study: controlled clinical trial

Free full text   (https://www.frontiersin.org/articles/10.3389/fnetp.2023.1205476/full)

Keywords:

brain networks [1]
controlled clinical trial [316]
enteric nervous system [4]
epilepsy [9]
gut-brain axis [5]
vagus nerve [6]
visceral osteopathy [81]

Abstract:

Non-invasive transcutaneous vagus nerve stimulation elicits similar therapeutic effects as invasive vagus nerve stimulation, offering a potential treatment alternative for a wide range of diseases, including epilepsy. Here, we present a novel, non-invasive stimulation of the vagus nerve, which is performed manually viscero-osteopathically on the abdomen (voVNS). We explore the impact of short-term voVNS on various local and global characteristics of EEG-derived, large-scale evolving functional brain networks from a group of 20 subjects with and without epilepsy. We observe differential voVNS-mediated alterations of these characteristics that can be interpreted as a reconfiguration and modification of networks and their stability and robustness properties. Clearly, future studies are necessary to assess the impact of such a non-pharmaceutical intervention on clinical decision-making in the treatment of epilepsy. However, our findings may add to the current discussion on the importance of the gut-brain axis in health and disease.


Search results      Copy URL to E-Mail

 
 
 






  • ImpressumLegal noticeDatenschutz


ostlib.de/data_rumwpbhsenjxadtzgfqc



Supported by

OSTLIB recommends