Advanced search


Search results        Search results      Copy URL to E-Mail


Reproducibility Assessment of the Response to CV4 as Measured by the Laser Doppler Flowmeter and Electrocardiogram

Journal: The Journal of the American Osteopathic Association Date: 2007/08, 107(8):Pages: 332. doi: Subito , type of study: pretest posttest design

Full text    (https://www.degruyter.com/document/doi/10.7556/jaoa.2007.107.8.327/html)

Keywords:

autonomic nervous system [142]
cranio-sacral osteopathy [223]
CV4 technique [14]
pretest posttest design [217]

Abstract:

Background: Osteopathic manipulation techniques, such as Compression of Fourth Ventricle (CV4), have been shown to influence autonomic balance as measured by Laser Doppler Flowmeter (LDF) and electrocardiogram (EKG). In this study, authors assess reproducibility of a subject's response to CV4, measured by LDF and EKG. Objective: Assess reproducibility of subject's response (change in autonomic variability) to CV4 by an alternate operator as compared to response elicited by reference standard operator. Methods: 22 healthy volunteers were enrolled in IRB approved project. Simultaneous LDF and EKG readings were obtained before, during, after CV4 in 7min segments. Five minutes of data with least amount of noise were selected from each segment for analysis. Each subject underwent this protocol on 2 different occasions, once each with reference standard operator and an alternate operator. All operators were trained in CV4 technique. Timed periods were compared using WINDAQ and BIOPAC software for LDF and Heart Rate Variability (HRV) software used for EKG. Spectral analyses were performed using Discrete Fourier Transformation and areas under the curve of the low frequency Traube-Hering wave (TH) (0.8-.15 Hz) were measured. Results were analyzed using a paired samples t-test in SPSS. Duration of change in area under curve of TH wave during CV4 performed by each operator was compared using a paired samples correlation in SPSS. Results: Paired samples t-test (SPSS) demonstrated significant (p<.05) decrease in autonomic variability from baseline for all subjects measured by LDF and EKG, regardless of the operator. Results of alternate operator were compared with results of primary investigator for each subject. Overall, there was no significant difference (p>.2) in the subject's response to CV4. Comparison of duration (seconds) of change, determined by a 40% decrease from baseline in area under curve (TH) during CV4 revealed correlation of .777 p=.001. Conclusion: Decreased autonomic variability and length of its duration during CV4 are reproducible in same subject by an alternate operator as compared to response elicited by reference operator. This response to CV4 as measured by LDF was mirrored in changes seen in HRV, as obtained from EKG. Any potential therapeutic effects of CV4 are undetermined at this time, it is recommended that LDF or EKG be used in clinical outcomes studies to investigate efficacy of CV4 in select patient populations.


Search results      Copy URL to E-Mail

 
 
 






  • ImpressumLegal noticeDatenschutz


ostlib.de/data_macbvkftqhgswpzjxure



Supported by

OSTLIB recommends